Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MGAM | O43451 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15720392 | 0.96 | LMNA (0.46) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL24565178 | 0.94 | USP2 (0.42) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL30530672 | 0.79 | ALOX15 (0.39) | LMNACYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL8677620 | 0.79 | TDP1 (0.50) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL8677624 | 0.79 | TDP1 (0.50) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL8469643 | 0.79 | MPI (0.35) | LMNACYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL7170688 | 0.78 | PDE4A (0.52) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL1403805 | 0.78 | PDE4A (0.52) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL3810811 | 0.78 | PDE4A (0.52) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL3705601 | 0.78 | LMNA (0.44) | TDP1LMNAL3MBTL1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772617-B1 | 7-O-CARBAMOYL HEPTOSE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AND SCREENING PROCESS FOR THEIR DETECTION | FORSCH BORSTEL INST FUER EXPER (DE) | 1999-06-23 | — | — | EP | disclosed |
| US-5798343-A | TREATING GRAM-NEGATIVE BACTERIA WITH HYDROFLUORIC ACID, HYDROLYZING OR METHOLYZING, PERMETHYLATING | FORSCHUNGSINSTITUT BORSTEL INSTITUT FUR EXPERIMENTELLE BIOLOGIE UND MEDIZIN (DE) | 1998-08-25 | — | — | US | disclosed |