Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21128809 | 0.86 | TP53 (0.49) | TP53KDM4ETDP1LMNAHIF1A | |
| SCHEMBL25493745 | 0.76 | TP53 (0.47) | TP53KDM4ETDP1LMNAHIF1A | |
| SCHEMBL21098282 | 0.74 | TP53 (0.49) | TP53KDM4ETDP1LMNAHIF1A | |
| SCHEMBL30694104 | 0.74 | TP53 (1.00) | TP53KDM4ETDP1LMNAHIF1A | |
| SCHEMBL2852298 | 0.74 | TP53 (1.00) | TP53KDM4ETDP1LMNAHIF1A | |
| SCHEMBL29767699 | 0.74 | TP53 (1.00) | TP53KDM4ETDP1LMNAHIF1A | |
| SCHEMBL19155631 | 0.73 | KDM4E (0.50) | KDM4ELMNACYP1A2POLBP4HTM | |
| SCHEMBL21743332 | 0.73 | KDM4E (0.50) | TP53KDM4ETDP1LMNAHIF1A | |
| SCHEMBL18792399 | 0.72 | ATM (0.37) | KDM4ETDP1LMNACYP1A2POLB | |
| SCHEMBL21903022 | 0.72 | TP53 (0.42) | TP53KDM4ETDP1LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782823-B1 | TIRES | SUMITOMO RUBBER IND (JP) | 2022-06-29 | — | — | EP | disclosed |