Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21098282 | 0.88 | TP53 (0.49) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL21128809 | 0.80 | TP53 (0.49) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL24565502 | 0.72 | TP53 (0.55) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL25493745 | 0.69 | TP53 (0.47) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL25525738 | 0.65 | KDM4E (0.45) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL19155573 | 0.65 | CES2 (0.41) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL29767699 | 0.65 | TP53 (1.00) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL30694104 | 0.65 | TP53 (1.00) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL2852298 | 0.65 | TP53 (1.00) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL18792258 | 0.64 | AKT1 (0.38) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3501846-B1 | RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE | SUMITOMO RUBBER IND (JP) | 2020-04-22 | — | — | EP | disclosed |