Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | CCR8 | P51685 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21098282 | 0.89 | TP53 (0.49) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL24565502 | 0.86 | TP53 (0.55) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL21903022 | 0.80 | TP53 (0.42) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL23046369 | 0.76 | KDM4E (0.44) | KDM4ETDP1SMN1; SMN2LMNAHTT | |
| SCHEMBL19085444 | 0.76 | AKT1 (0.38) | TDP1ATMALDH1A1MAPK1 | |
| SCHEMBL25493745 | 0.75 | TP53 (0.47) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL2852298 | 0.70 | TP53 (1.00) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL30694104 | 0.70 | TP53 (1.00) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL29767699 | 0.70 | TP53 (1.00) | TP53KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL22334346 | 0.70 | L3MBTL1 (0.35) | TP53SMN1; SMN2LMNAHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3597696-B1 | RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE | SUMITOMO RUBBER IND (JP) | 2023-05-17 | — | — | EP | disclosed |
| US-20190185643-A1 | RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2019-06-20 | — | — | US | disclosed |