Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24567066 | 0.88 | ESR1 (0.36) | MAPTALDH1A1CA9TSHRESR1 | |
| SCHEMBL2586996 | 0.88 | MAPT (0.52) | MAPTALDH1A1GAALMNACA9 | |
| SCHEMBL29073234 | 0.88 | OPRD1 (0.38) | MAPTALDH1A1TSHRESR1DHFR | |
| SCHEMBL24567068 | 0.87 | ESR1 (0.36) | MAPTALDH1A1GAALMNATSHR | |
| SCHEMBL24567372 | 0.86 | OPRD1 (0.39) | MAPTALDH1A1TSHRESR1DHFR | |
| SCHEMBL29737325 | 0.86 | OPRD1 (0.39) | MAPTALDH1A1TSHRESR1DHFR | |
| SCHEMBL24566827 | 0.84 | UCHL3 (0.42) | MAPTALDH1A1GAARAB9ANPSR1 | |
| SCHEMBL24567371 | 0.82 | UCHL3 (0.42) | MAPTALDH1A1GAALMNATSHR | |
| SCHEMBL762101 | 0.81 | ESR1 (0.47) | MAPTALDH1A1GAALMNAESR1 | |
| SCHEMBL29275080 | 0.81 | DHFR (0.46) | MAPTALDH1A1GAALMNADHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136020-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INTERNATIONAL (FR) | 2022-06-30 | — | — | WO | disclosed |