Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24567217 | 0.84 | TMIGD3 (0.37) | BRPF1GAA | |
| SCHEMBL24007634 | 0.72 | KDM4E (0.44) | KDM4EMITFALDH1A1HPGDKLF5 | |
| SCHEMBL24007902 | 0.69 | KDM4E (0.41) | KDM4EMITFALDH1A1HPGDKLF5 | |
| SCHEMBL24567228 | 0.68 | KDM4C (0.36) | KDM4EMITFALDH1A1HPGDKLF5 | |
| SCHEMBL24567209 | 0.68 | KDM4C (0.36) | KDM4EMITFALDH1A1HPGDKLF5 | |
| SCHEMBL24815180 | 0.63 | KDM4E (0.35) | KDM4EMITFALDH1A1HPGDKLF5 | |
| SCHEMBL18383188 | 0.60 | ALDH1A1 (0.43) | KDM4EMITFALDH1A1HPGDKLF5 | |
| SCHEMBL18387539 | 0.60 | L3MBTL1 (0.42) | KDM4EMITFALDH1A1HPGDKLF5 | |
| SCHEMBL24007637 | 0.58 | ADORA1 (0.46) | KDM4EMITFALDH1A1HPGDKLF5 | |
| SCHEMBL18260522 | 0.57 | KDM4E (0.39) | KDM4EMITFALDH1A1HPGDKLF5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140527-A1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | AJAX THERAPEUTICS, INC. (US) | 2022-06-30 | — | — | WO | disclosed |