Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12309130 | 1.00 | ADRB2 (0.32) | ADRB2ADRB1ADRB3MALT1BCDIN3D | |
| SCHEMBL24568077 | 1.00 | ADRB2 (0.32) | ADRB2ADRB1ADRB3MALT1BCDIN3D | |
| SCHEMBL25554183 | 0.79 | — | — | |
| SCHEMBL2912240 | 0.79 | — | — | |
| SCHEMBL20842263 | 0.76 | — | — | |
| SCHEMBL28469459 | 0.76 | MALT1 (0.32) | MALT1BCDIN3D | |
| SCHEMBL23866584 | 0.75 | MALT1 (0.39) | MALT1 | |
| SCHEMBL23866590 | 0.75 | MALT1 (0.39) | MALT1 | |
| SCHEMBL12413659 | 0.75 | MALT1 (0.39) | MALT1 | |
| SCHEMBL293678 | 0.75 | PLG (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |