⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912240 | 1.00 | — | — | |
| SCHEMBL20842263 | 0.81 | — | — | |
| SCHEMBL2918020 | 0.80 | — | — | |
| SCHEMBL28469459 | 0.80 | MALT1 (0.32) | — | |
| SCHEMBL23936838 | 0.79 | — | — | |
| SCHEMBL16919224 | 0.79 | — | — | |
| SCHEMBL17705680 | 0.79 | — | — | |
| SCHEMBL24568077 | 0.79 | ADRB2 (0.32) | — | |
| SCHEMBL12257130 | 0.79 | BCDIN3D (0.33) | — | |
| SCHEMBL24567798 | 0.79 | ADRB2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159532-A1 | PARATHYROID HORMONE (PTH) RECEPTOR ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2023-05-25 | — | — | US | disclosed |