SCHEMBL28469459

SCHEMBL28469459

CCNCC1COCCN1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 1/20 0.32
BCDIN3D Q7Z5W3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7518979 0.85 POLB (0.33) MALT1BCDIN3D
SCHEMBL7509521 0.82 GNAI3 (0.38)
SCHEMBL25554183 0.80
SCHEMBL2912240 0.80
SCHEMBL7505210 0.80 GNAI3 (0.46)
SCHEMBL35210850 0.78 MALT1 (0.33) MALT1
SCHEMBL35210843 0.78 MALT1 (0.33) MALT1
SCHEMBL20842263 0.78
Methylamine SCHEMBL28790382 0.78 ARG1 (0.31)
SCHEMBL16953 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114369094-A Trifluoromethyl substituted sulfonamide selective BCL-2 inhibitors 正大天晴药业集团股份有限公司 2022-04-19 CN disclosed
CN-111868059-B Trifluoromethyl substituted sulfonamide selective BCL-2 inhibitors 正大天晴药业集团股份有限公司 2021-12-03 CN disclosed
CN-111868059-A Trifluoromethyl substituted sulfonamide selective BCL-2 inhibitors 正大天晴药业集团股份有限公司 2020-10-30 CN disclosed