Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24568535 | 0.88 | PADI4 (0.31) | PADI4 | |
| SCHEMBL24568637 | 0.83 | PADI4 (0.30) | PADI4 | |
| SCHEMBL24568636 | 0.80 | ADORA3 (0.34) | PADI4 | |
| SCHEMBL24568633 | 0.78 | PADI4 (0.30) | PADI4 | |
| SCHEMBL31488220 | 0.68 | PADI4 (0.43) | PADI4 | |
| SCHEMBL31488120 | 0.65 | PADI4 (0.38) | PADI4 | |
| SCHEMBL24568059 | 0.65 | PADI4 (0.52) | PADI4 | |
| SCHEMBL31488201 | 0.65 | PADI4 (0.41) | PADI4 | |
| SCHEMBL31488104 | 0.65 | PADI4 (0.36) | PADI4 | |
| SCHEMBL29642198 | 0.65 | PADI4 (0.52) | PADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |