Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24568534 | 0.88 | GRIA2 (0.32) | PADI4 | |
| SCHEMBL24568637 | 0.85 | PADI4 (0.30) | PADI4 | |
| SCHEMBL24568636 | 0.82 | ADORA3 (0.34) | PADI4 | |
| SCHEMBL24568633 | 0.80 | PADI4 (0.30) | PADI4 | |
| SCHEMBL24567704 | 0.69 | PADI4 (0.53) | PADI4 | |
| SCHEMBL24568064 | 0.69 | PADI4 (0.52) | PADI4 | |
| SCHEMBL24568063 | 0.65 | PDE5A (0.33) | — | |
| SCHEMBL24797436 | 0.62 | PTGS2 (0.51) | — | |
| SCHEMBL23777027 | 0.58 | NOTUM (0.40) | — | |
| SCHEMBL20853161 | 0.54 | PLK1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |