Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.50 |
| ▸ | FAP | Q12884 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856403 | 1.00 | PREP (0.50) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2856039 | 1.00 | PREP (0.50) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2801067 | 0.87 | FDPS (0.57) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2865570 | 0.85 | PREP (0.48) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL24568251 | 0.82 | ALDH1A1 (0.53) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL24571395 | 0.82 | ALDH1A1 (0.53) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10491673 | 0.81 | PREP (0.46) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2859570 | 0.81 | PREP (0.50) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL24571697 | 0.79 | FDPS (0.43) | FDPSMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL2859373 | 0.79 | CTSA (0.53) | TAS1R3TAS1R1FDPSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |