Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24568404 | 0.89 | ACVR1B (0.33) | PTGES | |
| SCHEMBL24568731 | 0.81 | TGFBR1 (0.30) | — | |
| SCHEMBL24568837 | 0.76 | RET (0.30) | — | |
| SCHEMBL24569030 | 0.73 | AGPAT2 (0.38) | PTGES | |
| SCHEMBL24569039 | 0.69 | TGFBR1 (0.36) | PTGES | |
| SCHEMBL24568790 | 0.67 | HPGD (0.44) | — | |
| SCHEMBL27200492 | 0.66 | TGFBR1 (0.47) | — | |
| SCHEMBL27030857 | 0.65 | CXCL12 (0.38) | PTGES | |
| SCHEMBL16879402 | 0.65 | TGFBR1 (0.39) | — | |
| SCHEMBL24568794 | 0.64 | CYP11B1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136221-A1 | PYRIDO OXAZINE DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-06-30 | — | — | WO | disclosed |