Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24568397 | 0.86 | KMO (0.30) | — | |
| SCHEMBL24568311 | 0.85 | RET (0.31) | RET | |
| SCHEMBL24568803 | 0.85 | TGFBR1 (0.30) | RET | |
| SCHEMBL24568415 | 0.83 | — | — | |
| SCHEMBL24568102 | 0.83 | TGFBR1 (0.32) | RET | |
| SCHEMBL24568424 | 0.80 | CHRM2 (0.31) | — | |
| SCHEMBL24568273 | 0.77 | TGFBR1 (0.35) | RET | |
| SCHEMBL24569044 | 0.76 | EGFR (0.38) | RET | |
| SCHEMBL29694459 | 0.76 | EGFR (0.38) | RET | |
| SCHEMBL24568404 | 0.76 | ACVR1B (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136221-A1 | PYRIDO OXAZINE DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-06-30 | — | — | WO | disclosed |