Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1B | P36896 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24568795 | 0.89 | PTGES (0.31) | PTGES | |
| SCHEMBL24568837 | 0.76 | RET (0.30) | — | |
| SCHEMBL24568731 | 0.76 | TGFBR1 (0.30) | ACVR1BTGFBR1ACVRL1 | |
| SCHEMBL24568805 | 0.73 | AGPAT2 (0.41) | ACVR1BTGFBR1ACVRL1AGPAT2 | |
| SCHEMBL24569028 | 0.73 | HSP90AA1 (0.40) | ACVR1BTGFBR1ACVRL1PTGESAGPAT2 | |
| SCHEMBL24568807 | 0.71 | AMY1A (0.40) | ACVR1BTGFBR1ACVRL1AGPAT2 | |
| SCHEMBL29694366 | 0.71 | AMY1A (0.40) | ACVR1BTGFBR1ACVRL1AGPAT2 | |
| SCHEMBL28994427 | 0.68 | TGFBR1 (0.46) | ACVR1BTGFBR1ACVRL1 | |
| SCHEMBL24568403 | 0.65 | KDM4E (0.47) | ACVR1BTGFBR1ACVRL1 | |
| SCHEMBL24569030 | 0.64 | AGPAT2 (0.38) | TGFBR1PTGESAGPAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136221-A1 | PYRIDO OXAZINE DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-06-30 | — | — | WO | disclosed |