SCHEMBL245690

SCHEMBL245690

[CH2]COc1cc(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.43
AKR1B1 P15121 1/20 0.40
HPGD P15428 2/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 2/20 0.36
HSP90AA1 P07900 1/20 0.36
NR1I2 O75469 1/20 0.34
ADRA2A P08913 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
TACR2 P21452 1/20 0.34
DRD1 P21728 1/20 0.34
SLC6A2 P23975 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
ADORA1 P30542 1/20 0.34
SLC6A4 P31645 1/20 0.34
OPRM1 P35372 1/20 0.34
DRD3 P35462 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL243080 0.77 MRGPRX4 (0.41) CYP3A4HPGDTSHRHTR2AHTR2C
SCHEMBL11511184 0.76 NR1I2 (0.50) TSHRHSD17B10NR1I2ADRA2AADORA3
SCHEMBL10715975 0.72 AKR1B1 (0.61) CYP3A4AKR1B1HPGDTSHRHSD17B10
SCHEMBL9489300 0.71 TDP1 (0.56) HPGDTSHRHSD17B10GALEALDH1A1
SCHEMBL23709935 0.70 RHEB (0.51) CYP3A4TACR2SLC6A4
SCHEMBL11512582 0.70 NR1I2 (0.36) TSHRNR1I2ADRA2AADORA3ADRA2B
SCHEMBL20678889 0.69 ALDH1A1 (0.46) CYP3A4AKR1B1HPGDTSHRALDH1A1
SCHEMBL914797 0.69 CYP3A4 (0.50) CYP3A4AKR1B1HPGDTSHRHSD17B10
SCHEMBL29749799 0.69 CYP3A4 (0.50) CYP3A4AKR1B1HPGDTSHRHSD17B10
SCHEMBL15169353 0.67 THRB (0.49) CYP3A4AKR1B1HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220040914-A1 FUNCTIONALIZED PRODUCT FABRICATED FROM A RESIN COMPRISING A FUNCTIONAL COMPONENT AND A POLYMERIC RESIN, AND METHOD OF MAKING THE SAME NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2022-02-10 US claimed
WO-2020079669-A1 FUNCTIONALIZED PRODUCT FABRICATED FROM A RESIN COMPRISING A FUNCTIONAL COMPONENT AND A POLYMERIC RESIN, AND METHOD OF MAKING THE SAME NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2020-04-23 WO claimed
US-20160122581-A1 POLYMER COMPOSITIONS AND COATINGS FOR FOOD AND BEVERAGE PACKAGING THE COCA-COLA COMPANY (US) 2016-05-05 US claimed
EP-2997094-A1 POLYMER COMPOSITIONS AND COATINGS FOR FOOD AND BEVERAGE PACKAGING The Coca-Cola Company (US) 2016-03-23 EP claimed
WO-2014186285-A1 POLYMER COMPOSITIONS AND COATINGS FOR FOOD AND BEVERAGE PACKAGING THE COCA-COLA COMPANY (US) 2014-11-20 WO claimed
WO-2024125573-A1 PHOTOCURABLE COMPOSITION, AND PHOTOCURABLE COMPOSITION FOR 3D PRINTING AND USE THEREOF 常州强力电子新材料股份有限公司 2024-06-20 WO disclosed
CN-118185278-A Photo-curing composition, 3D printing photo-curing composition and application thereof 常州强力电子新材料股份有限公司 2024-06-14 CN disclosed
US-20240117103-A1 POLYMER, METHOD OF PREPARING SAME, AND POLYURETHANE PREPARED BY USING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2024-04-11 US disclosed
CN-110007563-B Negative photosensitive resin composition, spacer, protective film, and liquid crystal display element 奇美实业股份有限公司 2024-04-02 CN disclosed
US-11940634-B2 3D printed antenna CARLETON UNIVERSITY (CA) 2024-03-26 US disclosed
EP-4339218-A1 POLYMER, METHOD OF PREPARING SAME, AND POLYURETHANE PREPARED BY USING SAME Seoul National University R & DB Foundation (KR) 2024-03-20 EP disclosed
CN-117700588-A Polymer, method for preparing polymer and polyurethane prepared by using polymer 首尔大学校产学协力团 2024-03-15 CN disclosed
EP-0848293-A1 Photo-curable resin composition DSM N.V. (NL) 1998-06-17 EP disclosed
EP-0848292-A1 Photo-curable resin composition DSM N.V. (NL) 1998-06-17 EP disclosed
EP-0837366-A1 Photocurable resin composition DSM N.V. (NL) 1998-04-22 EP disclosed
EP-0831373-A2 Photo-curable resin compositions and process for preparing a resin-based mold DSM N.V. (NL) 1998-03-25 EP disclosed
EP-0830928-A2 Resin composition and mold made from such resin, for forming fibrous material DSM N.V. (NL) 1998-03-25 EP disclosed
WO-1998001778-A1 RADIATION CURABLE RESIN COMPOSITION DSM N.V. (NL) 1998-01-15 WO disclosed
WO-1997047671-A1 RADIATION CURABLE RESIN COMPOSITION DSM N.V. (NL) 1997-12-18 WO disclosed
WO-1997038354-A1 PHOTO-CURABLE RESIN COMPOSITION DSM N.V. (NL) 1997-10-16 WO disclosed