SCHEMBL243080

SCHEMBL243080

[CH2]COc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 2/20 0.41
GPR84 Q9NQS5 1/20 0.41
CYP3A4 P08684 2/20 0.36
MAPK1 P28482 2/20 0.36
HTR2A P28223 6/20 0.34
HTR2C P28335 6/20 0.34
ALDH1A1 P00352 3/20 0.32
TP53 P04637 2/20 0.32
TSHR P16473 2/20 0.32
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
CYP2C9 P11712 2/20 0.32
KMT2A Q03164 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
FABP3 P05413 1/20 0.32
ABCC3 O15438 1/20 0.32
PLIN1 O60240 1/20 0.32
LMNA P02545 1/20 0.32
GSTA1 P08263 1/20 0.32
GSTP1 P09211 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1547294 0.80 ALDH1A1 (0.49) MRGPRX4CYP3A4ALDH1A1TP53TSHR
SCHEMBL8778565 0.78 MRGPRX4 (0.43) MRGPRX4GPR84CYP3A4MAPK1HTR2A
SCHEMBL12300309 0.77 L3MBTL1 (0.42) MRGPRX4GPR84MAPK1HTR2AHTR2C
SCHEMBL2097928 0.77 MRGPRX4 (0.45) MRGPRX4GPR84CYP3A4MAPK1HTR2A
SCHEMBL11880335 0.77 MRGPRX4 (0.41) MRGPRX4GPR84CYP3A4MAPK1HTR2A
SCHEMBL2097932 0.77 MRGPRX4 (0.45) MRGPRX4GPR84CYP3A4MAPK1HTR2A
SCHEMBL245690 0.77 CYP3A4 (0.43) CYP3A4MAPK1HTR2AHTR2CALDH1A1
SCHEMBL28627196 0.77 HTR2C (0.55) MRGPRX4GPR84MAPK1HTR2AHTR2C
SCHEMBL7228434 0.76 GPR84 (0.47) MRGPRX4GPR84CYP3A4MAPK1HTR2A
SCHEMBL28826984 0.74 CSNK2A1 (0.51) MRGPRX4GPR84MAPK1HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220040914-A1 FUNCTIONALIZED PRODUCT FABRICATED FROM A RESIN COMPRISING A FUNCTIONAL COMPONENT AND A POLYMERIC RESIN, AND METHOD OF MAKING THE SAME NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2022-02-10 US claimed
WO-2020079669-A1 FUNCTIONALIZED PRODUCT FABRICATED FROM A RESIN COMPRISING A FUNCTIONAL COMPONENT AND A POLYMERIC RESIN, AND METHOD OF MAKING THE SAME NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2020-04-23 WO claimed
WO-2024125573-A1 PHOTOCURABLE COMPOSITION, AND PHOTOCURABLE COMPOSITION FOR 3D PRINTING AND USE THEREOF 常州强力电子新材料股份有限公司 2024-06-20 WO disclosed
CN-118185278-A Photo-curing composition, 3D printing photo-curing composition and application thereof 常州强力电子新材料股份有限公司 2024-06-14 CN disclosed
US-20240117103-A1 POLYMER, METHOD OF PREPARING SAME, AND POLYURETHANE PREPARED BY USING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2024-04-11 US disclosed
US-11940634-B2 3D printed antenna CARLETON UNIVERSITY (CA) 2024-03-26 US disclosed
EP-4339218-A1 POLYMER, METHOD OF PREPARING SAME, AND POLYURETHANE PREPARED BY USING SAME Seoul National University R & DB Foundation (KR) 2024-03-20 EP disclosed
CN-117700588-A Polymer, method for preparing polymer and polyurethane prepared by using polymer 首尔大学校产学协力团 2024-03-15 CN disclosed
CN-107463067-B Black photosensitive resin composition and application thereof 奇美实业股份有限公司 2024-01-26 CN disclosed
US-20230322998-A1 PHOTO-CURABLE RESIN COMPOSITION FOR USE IN STEREOLITHOGRAPHY BLUE CUBE IP LLC 2023-10-12 US disclosed
WO-2023178414-A1 3D-PRINTABLE PIEZOELECTRIC CERAMIC COMPOSITIONS WITH CARBON NANOMATERIALS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2023-09-28 WO disclosed
EP-0848292-A1 Photo-curable resin composition DSM N.V. (NL) 1998-06-17 EP disclosed
EP-0848294-A1 Photo-curable resin composition used for photo-fabrication of three-dimensional objects DSM N.V. (NL) 1998-06-17 EP disclosed
EP-0848293-A1 Photo-curable resin composition DSM N.V. (NL) 1998-06-17 EP disclosed
EP-0837366-A1 Photocurable resin composition DSM N.V. (NL) 1998-04-22 EP disclosed
EP-0831373-A2 Photo-curable resin compositions and process for preparing a resin-based mold DSM N.V. (NL) 1998-03-25 EP disclosed
EP-0830928-A2 Resin composition and mold made from such resin, for forming fibrous material DSM N.V. (NL) 1998-03-25 EP disclosed
WO-1998001778-A1 RADIATION CURABLE RESIN COMPOSITION DSM N.V. (NL) 1998-01-15 WO disclosed
WO-1997047671-A1 RADIATION CURABLE RESIN COMPOSITION DSM N.V. (NL) 1997-12-18 WO disclosed
WO-1997038354-A1 PHOTO-CURABLE RESIN COMPOSITION DSM N.V. (NL) 1997-10-16 WO disclosed