SCHEMBL24569288

SCHEMBL24569288

Cc1c(Cl)cccc1C(C)c1cccc(Cl)c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
CYP1A2 P05177 3/20 0.50
CYP3A4 P08684 3/20 0.50
CYP2D6 P10635 1/20 0.50
NFKB1 P19838 1/20 0.50
PNMT P11086 1/20 0.50
LMNA P02545 4/20 0.48
GLA P06280 1/20 0.48
CYP2A6 P11509 1/20 0.38
RAPGEF4 Q8WZA2 1/20 0.37
MAPT P10636 1/20 0.37
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
TSHR P16473 3/20 0.37
FAAH O00519 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
GABRA1 P14867 1/20 0.37
HPGD P15428 1/20 0.37
GABRB1 P18505 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2737309 0.88 CYP1A2 (0.48) ALDH1A1CYP1A2CYP3A4CYP2D6NFKB1
SCHEMBL1281895 0.84 P2RX7 (0.47) ALDH1A1CYP1A2CYP3A4CYP2D6NFKB1
SCHEMBL16954732 0.84 CYP1A2 (0.45) ALDH1A1CYP1A2CYP3A4CYP2D6NFKB1
SCHEMBL23526499 0.84 CYP3A4 (0.67) ALDH1A1CYP1A2CYP3A4CYP2D6NFKB1
SCHEMBL1467055 0.84 CYP3A4 (0.67) ALDH1A1CYP1A2CYP3A4CYP2D6NFKB1
SCHEMBL23563480 0.81 ALDH1A1 (0.52) ALDH1A1CYP1A2CYP3A4CYP2D6NFKB1
SCHEMBL18567934 0.81 CYP1A2 (0.42) ALDH1A1CYP1A2CYP3A4CYP2D6NFKB1
SCHEMBL22801396 0.80 CYP1A2 (0.68) ALDH1A1CYP1A2CYP3A4CYP2D6NFKB1
SCHEMBL12204154 0.79 ADRB2 (0.48) ALDH1A1CYP1A2CYP3A4CYP2D6NFKB1
SCHEMBL20847708 0.79 CYP1A2 (0.41) ALDH1A1CYP1A2CYP3A4CYP2D6NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220204766-A1 HIGH MOLECULAR WEIGHT FLEXIBLE CURABLE POLYIMIDES DESIGNER MOLECULES, INC 2022-06-30 US disclosed