Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 7/20 | 0.42 |
| ▸ | ATP4B | P51164 | 7/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL484346 | 0.74 | BCHE (0.42) | POLBTRPV1ALDH1A1MEN1KMT2A | |
| SCHEMBL484407 | 0.73 | ALDH1A1 (0.53) | POLBTRPV1ALDH1A1MEN1KMT2A | |
| SCHEMBL6209371 | 0.70 | TRPV1 (0.51) | POLBTRPV1ALDH1A1MEN1KMT2A | |
| SCHEMBL21974450 | 0.69 | ALDH1A1 (0.44) | POLBTRPV1ALDH1A1MEN1KMT2A | |
| SCHEMBL12403302 | 0.68 | RAB9A (0.49) | POLBTRPV1ALDH1A1MEN1KMT2A | |
| SCHEMBL484268 | 0.65 | SNCA (0.54) | TRPV1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3081165 | 0.61 | ALDH1A1 (0.54) | POLBALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL2162639 | 0.61 | ALDH1A1 (0.54) | POLBALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL6474677 | 0.60 | NPC1 (0.64) | ATP4AATP4BALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28127452 | 0.59 | POLB (0.72) | POLBNPC1RAB9APKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550255-A1 | IMAGING AGENTS FOR DETECTING NEUROLOGICAL DISORDERS | Siemens Medical Solutions USA, Inc. (US) | 2013-01-30 | — | — | EP | disclosed |
| WO-2011119565-A1 | IMAGING AGENTS FOR DETECTING NEUROLOGICAL DISORDERS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2011-09-29 | — | — | WO | disclosed |