SCHEMBL484346

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12324095	0.76	KDM4E (0.57)	ALDH1A1POLBKDM4EHSD17B10RAB9A
	SCHEMBL6209371	0.76	TRPV1 (0.51)	TSHRALDH1A1POLBKDM4EHSD17B10
	SCHEMBL483811	0.74	TTR (0.45)	ALDH1A1KDM4ERAB9AMAPTNPC1
	SCHEMBL2457129	0.74	ATP4A (0.42)	ALDH1A1POLBKDM4EHSD17B10TRPV1
	SCHEMBL12403302	0.74	RAB9A (0.49)	ALDH1A1POLBKDM4EHSD17B10TRPV1
	SCHEMBL484407	0.74	ALDH1A1 (0.53)	ALDH1A1POLBKDM4EHSD17B10TRPV1
	SCHEMBL484157	0.71	APP (0.49)	ALDH1A1POLBKDM4EKLK1KLK5
	SCHEMBL484268	0.70	SNCA (0.54)	ALDH1A1KDM4EHSD17B10TRPV1RAB9A
	SCHEMBL21974450	0.69	ALDH1A1 (0.44)	ALDH1A1POLBKDM4EHSD17B10TRPV1
	SCHEMBL2162639	0.65	ALDH1A1 (0.54)	BCHEALDH1A1POLBKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.