Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538809 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KDM4ESMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL10050008 | 0.74 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL14541695 | 0.73 | NQO2 (0.52) | ALDH1A1KDM4ESMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL4343079 | 0.71 | NQO2 (0.53) | ALDH1A1KDM4ESMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL15827525 | 0.70 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL15217982 | 0.69 | ALDH1A1 (0.77) | ALDH1A1KDM4ESMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL15213964 | 0.69 | ALDH1A1 (1.00) | ALDH1A1KDM4ESMN1; SMN2CYP2C19CYP1A2 | |
| P-Xylene SCHEMBL28247604 | 0.69 | ACHE (0.50) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8233351 | 0.68 | AGXT (0.54) | ALDH1A1KDM4ESMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL13680866 | 0.67 | ALDH1A1 (0.60) | ALDH1A1KDM4ESMN1; SMN2CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220202772-A1 | COMPOSITIONS AND METHODS FOR INHIBITING RIBOSOME INACTIVATING PROTEINS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2022-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220202772-A1 | COMPOSITIONS AND METHODS FOR INHIBITING RIBOSOME INACTIVATING PROTEINS | RACK1, RRBP1, RPL30 | ALDH1A1 3524/4885KDM4E 2155/4885SMN1; SMN2 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.