SCHEMBL2457362

SCHEMBL2457362

CCCCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCCCO)C(O)CO

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
MAPK1 P28482 1/20 0.55
LMNA P02545 4/20 0.50
PRKCA P17252 4/20 0.49
PRKCE Q02156 2/20 0.49
PRKCQ Q04759 2/20 0.49
PRKCD Q05655 2/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
KDM4E B2RXH2 1/20 0.48
DUSP3 P51452 1/20 0.48
PTPN1 P18031 1/20 0.47
ALDH1A1 P00352 1/20 0.45
DGKA P23743 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28452236 0.95 MAPT (0.60) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL7612157 0.95 MAPT (0.60) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL4442105 0.90 FFAR4 (0.55) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL27827822 0.87 PRKCA (0.59) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL2455851 0.87 PRKCA (0.59) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL15925833 0.86 LMNA (0.58) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL30932019 0.86 MAPT (0.64) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL22579234 0.86 MAPT (0.64) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL754093 0.86 MAPT (0.41) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL9298640 0.85 ALDH1A1 (0.69) MAPTMAPK1LMNAPRKCAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2367533-A1 SOLID COMPOSITION CONTAINING THE INGREDIENT RASAGILINE Ratiopharm GmbH (DE) 2011-09-28 EP claimed
WO-2010070090-A1 SOLID COMPOSITION CONTAINING THE INGREDIENT RASAGILINE RATIOPHARM GMBH (DE) 2010-06-24 WO claimed
EP-2367533-A1 SOLID COMPOSITION CONTAINING THE INGREDIENT RASAGILINE Ratiopharm GmbH (DE) 2011-09-28 EP disclosed
WO-2010070090-A1 SOLID COMPOSITION CONTAINING THE INGREDIENT RASAGILINE RATIOPHARM GMBH (DE) 2010-06-24 WO disclosed