Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.55 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.55 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butobendine SCHEMBL309587 | 1.00 | SCN1A (0.55) | SCN1ASCN2ASCN3ACYP3A4CYP2D6 | |
| Butobendine SCHEMBL1649028 | 0.99 | SCN1A (0.54) | SCN1ASCN2ASCN3ACYP3A4CYP2D6 | |
| SCHEMBL9910014 | 0.77 | SLC29A1 (0.56) | SCN1ASCN2ASCN3ACYP3A4CYP2D6 | |
| SCHEMBL11848930 | 0.76 | SLC29A1 (0.55) | SCN1ASCN2ASCN3ACYP3A4CYP2D6 | |
| Ethyltrimethoxy Benzoate SCHEMBL4410910 | 0.75 | KMT2A (0.66) | SCN1ASCN2ASCN3ACYP3A4CYP2D6 | |
| SCHEMBL2612552 | 0.75 | SLC29A1 (0.54) | SCN1ASCN2ASCN3ACYP3A4CYP2D6 | |
| SCHEMBL28969683 | 0.75 | SLC29A1 (0.54) | SCN1ASCN2ASCN3ACYP3A4CYP2D6 | |
| SCHEMBL2612567 | 0.75 | PTPN1 (0.68) | SCN1ASCN2ASCN3ACYP3A4CYP2D6 | |
| SCHEMBL10428055 | 0.74 | SLC29A1 (0.59) | SCN1ASCN2ASCN3ACYP3A4CYP2D6 | |
| SCHEMBL13183860 | 0.73 | TSHR (0.54) | SCN1ASCN2ASCN3ACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110224128-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF MUSCULAR DYSTROPHY | WHALEN ANNE | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224128-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF MUSCULAR DYSTROPHY | PYGM, TNNC1, MYOF | SCN1A 755/4885SCN2A 1235/4885SCN3A 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.