Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22860049 | 0.80 | PDCD1 (0.40) | — | |
| SCHEMBL24125131 | 0.78 | SSTR4 (0.30) | — | |
| SCHEMBL24576052 | 0.71 | HTR2A (0.37) | — | |
| SCHEMBL24124148 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL18321939 | 0.67 | CHRNB2 (0.37) | — | |
| SCHEMBL25961290 | 0.67 | PDK2 (0.33) | PDK2 | |
| Hydrochloric Acid SCHEMBL29404790 | 0.66 | CHRNB2 (0.36) | — | |
| SCHEMBL24576051 | 0.65 | HTR2A (0.44) | — | |
| 6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine SCHEMBL103669 | 0.64 | — | — | |
| 6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine SCHEMBL29617701 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140326-A1 | SUBSTITUTED INDOLE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |