Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24578299 | 0.82 | IKBKE (0.42) | IKBKETBK1 | |
| SCHEMBL24579094 | 0.79 | WNT1 (0.35) | — | |
| SCHEMBL24577112 | 0.78 | HDAC6 (0.34) | IKBKETBK1 | |
| SCHEMBL24577155 | 0.78 | IKBKE (0.34) | IKBKETBK1 | |
| Hydrochloric Acid SCHEMBL29759944 | 0.77 | IKBKE (0.36) | IKBKETBK1 | |
| Hydrochloric Acid SCHEMBL27185341 | 0.77 | IKBKE (0.36) | IKBKETBK1 | |
| SCHEMBL24577993 | 0.77 | MAPT (0.31) | — | |
| SCHEMBL24577132 | 0.76 | NAMPT (0.38) | — | |
| SCHEMBL24577200 | 0.76 | HDAC6 (0.33) | IKBKETBK1 | |
| SCHEMBL24578221 | 0.75 | RIPK2 (0.33) | IKBKETBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136509-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2022-06-30 | — | — | WO | disclosed |