Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24579051 | 0.98 | IRAK4 (0.31) | IRAK4ALDH1A1MEN1KMT2A | |
| SCHEMBL24579060 | 0.88 | KDM1A (0.31) | — | |
| SCHEMBL24577488 | 0.85 | — | — | |
| SCHEMBL24577841 | 0.85 | GSK3B (0.37) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL24579181 | 0.85 | — | — | |
| SCHEMBL24579106 | 0.84 | RAB9A (0.34) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL24578956 | 0.84 | — | — | |
| SCHEMBL24578957 | 0.84 | RAB9A (0.34) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL24577394 | 0.83 | POLB (0.33) | — | |
| SCHEMBL24577267 | 0.81 | WNT1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136509-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2022-06-30 | — | — | WO | disclosed |