Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24577175 | 0.82 | MET (0.33) | — | |
| SCHEMBL24577681 | 0.81 | KDM4E (0.34) | NPC1RAB9A | |
| SCHEMBL24578994 | 0.81 | MAPK8 (0.35) | — | |
| SCHEMBL24577305 | 0.81 | LCK (0.31) | — | |
| SCHEMBL24578956 | 0.80 | — | — | |
| SCHEMBL24577488 | 0.79 | — | — | |
| SCHEMBL24579060 | 0.78 | KDM1A (0.31) | — | |
| SCHEMBL24577394 | 0.78 | POLB (0.33) | — | |
| SCHEMBL24579106 | 0.78 | RAB9A (0.34) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24577021 | 0.72 | ALDH1A1 (0.33) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136509-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2022-06-30 | — | — | WO | disclosed |