Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29759921 | 1.00 | NR3C1 (0.34) | NR3C1IRAK4P2RX7MAOAMAOB | |
| SCHEMBL24577656 | 0.89 | NR3C1 (0.35) | NR3C1IRAK4P2RX7TSHRTDP1 | |
| SCHEMBL29759860 | 0.87 | NR3C1 (0.31) | NR3C1 | |
| SCHEMBL24577658 | 0.87 | NR3C1 (0.31) | NR3C1 | |
| SCHEMBL24577107 | 0.87 | NR3C1 (0.33) | NR3C1IRAK4 | |
| SCHEMBL29759558 | 0.86 | HDAC2 (0.32) | NR3C1 | |
| SCHEMBL24577652 | 0.86 | HDAC2 (0.32) | NR3C1 | |
| SCHEMBL29760011 | 0.85 | IKBKE (0.35) | NR3C1IRAK4 | |
| SCHEMBL24577968 | 0.85 | IKBKE (0.35) | NR3C1IRAK4 | |
| SCHEMBL24577629 | 0.85 | IKBKE (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136509-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2022-06-30 | — | — | WO | disclosed |