Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 5/20 | 0.51 |
| ▸ | G6PD | P11413 | 3/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8230178 | 0.74 | HDAC1 (1.00) | HDAC1HDAC7HDAC8HDAC6HDAC5 | |
| SCHEMBL24577995 | 0.71 | HDAC1 (0.70) | HDAC1HDAC7HDAC8HDAC6HDAC5 | |
| SCHEMBL79203 | 0.70 | CASP3 (1.00) | HDAC1HDAC7HDAC8HDAC6HDAC5 | |
| SCHEMBL24327914 | 0.68 | CASP3 (1.00) | HDAC1HDAC7HDAC8HDAC6HDAC5 | |
| SCHEMBL21846444 | 0.68 | CASP3 (0.81) | HDAC1HDAC7HDAC8HDAC6HDAC5 | |
| SCHEMBL8222491 | 0.68 | CASP3 (0.75) | HDAC1HDAC7HDAC8HDAC6HDAC5 | |
| SCHEMBL13606221 | 0.66 | G6PD (0.72) | HDAC1HDAC7HDAC8HDAC6HDAC5 | |
| SCHEMBL20022708 | 0.66 | CASP3 (0.77) | HDAC1HDAC7HDAC8HDAC6HDAC5 | |
| SCHEMBL2963555 | 0.64 | CASP3 (0.68) | FAAHMGLLCASP3G6PDKAT2A | |
| SCHEMBL13606231 | 0.64 | HDAC3 (0.72) | HDAC1HDAC7HDAC8HDAC6HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133551-A1 | HISTONE DEACETYLASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-06-30 | — | — | WO | disclosed |