SCHEMBL79203

SCHEMBL79203

O=c1c2ccccc2sn1Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 6/20 1.00
FAAH O00519 1/20 0.82
MGLL Q99685 1/20 0.82
HDAC3 O15379 1/20 0.65
HDAC4 P56524 1/20 0.65
HDAC1 Q13547 1/20 0.65
HDAC7 Q8WUI4 1/20 0.65
HDAC8 Q9BY41 1/20 0.65
HDAC6 Q9UBN7 1/20 0.65
HDAC9 Q9UKV0 1/20 0.65
HDAC5 Q9UQL6 1/20 0.65
KAT2B Q92831 3/20 0.61
KAT2A Q92830 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21846444 0.90 CASP3 (0.81) CASP3FAAHMGLLHDAC3HDAC4
SCHEMBL18872061 0.88 CASP3 (0.79) CASP3FAAHMGLLHDAC3HDAC4
SCHEMBL24327914 0.87 CASP3 (1.00) CASP3FAAHMGLLHDAC3HDAC4
SCHEMBL20022708 0.87 CASP3 (0.77) CASP3FAAHMGLLHDAC3HDAC4
SCHEMBL17515278 0.87 CASP3 (0.77) CASP3FAAHMGLLHDAC3HDAC4
SCHEMBL8222491 0.86 CASP3 (0.75) CASP3FAAHMGLLHDAC3HDAC4
SCHEMBL17515279 0.83 CASP3 (1.00) CASP3FAAHMGLLHDAC3HDAC4
SCHEMBL24327473 0.83 CASP3 (0.72) CASP3FAAHMGLLHDAC3HDAC4
SCHEMBL6550955 0.83 CASP3 (1.00) CASP3KAT2BKAT2A
SCHEMBL20022707 0.82 CASP3 (0.68) CASP3FAAHMGLLHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210060051-A1 COMBINED MODALITIES FOR NUCLEOSIDES AND/OR NADPH OXIDASE (NOX) INHIBITORS AS MYELOID-SPECIFIC ANTIVIRAL AGENTS EMORY UNIVERSITY 2021-03-04 US claimed
EP-3732180-A1 COMBINED MODALITIES FOR NUCLEOSIDES AND/OR NADPH OXIDASE (NOX) INHIBITORS AS MYELOID-SPECIFIC ANTIVIRAL AGENTS Emory University (US) 2020-11-04 EP claimed
WO-2011062864-A2 INHIBITORS OF NOX ENZYMES AND METHODS OF USE THEREOF EMORY UNIVERSITY (US) 2011-05-26 WO claimed
EP-3980400-B1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS UNIV EMORY (US) 2025-08-06 EP disclosed
US-20250114389-A1 NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS UNIV EMORY (US) 2025-04-10 US disclosed
US-12268723-B2 Peptidomimetics for the treatment of coronavirus and picorna virus infections EMORY UNIVERSITY (US) 2025-04-08 US disclosed
US-12239655-B2 Combined modalities for nucleosides and/or NADPH oxidase (NOX) inhibitors as myeloid-specific antiviral agents EMORY UNIVERSITY (US) 2025-03-04 US disclosed
US-20240238323-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES EMORY UNIVERSITY 2024-07-18 US disclosed
US-20240216413-A1 THIONUCLEOSIDES AS ANTIVIRAL AGENTS EMORY UNIVERSITY (US) 2024-07-04 US disclosed
CN-117881403-A Thionucleosides as antiviral agents 爱莫里大学 2024-04-12 CN disclosed
CN-117858711-A Nucleoside and nucleotide analogs as antiviral agents 爱莫里大学 2024-04-09 CN disclosed
EP-0506349-A1 Stabilising solution for lightsensitive silver halide color photographic material, and processing method making use of the stabilizing solution KONICA CORPORATION (JP) 1992-09-30 EP disclosed
EP-0227358-B1 HOUSING PACK FOR PHOTOGRAPHIC PROCESSING SOLUTION KONICA CORPORATION (JP) 1992-08-12 EP disclosed
EP-0476434-A2 Method for processing silver halide color photographic light sensitive materials KONICA CORPORATION (JP) 1992-03-25 EP disclosed
EP-0474461-A1 Method of processing light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1992-03-11 EP disclosed
US-4791013-A STORAGE AND WASTE COMPARTMENTS; OXYGEN BARRIER MEMBRANE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-12-13 US disclosed
US-4778746-A COLOR DEVELOPING, FIXING, STABILIZATION WITHOUT WASHING KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-10-18 US disclosed
US-4687731-A STORAGE STABILITY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-08-18 US disclosed
EP-0227358-A2 Housing pack for photographic processing solution KONICA CORPORATION (JP) 1987-07-01 EP disclosed
EP-0182566-A2 Method for processing lightsensitive silver halide color photographic material KONICA CORPORATION (JP) 1986-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216413-A1 THIONUCLEOSIDES AS ANTIVIRAL AGENTS MTAP, NSUN3, METTL3 CASP3 182/4885FAAH 3237/4885MGLL 3423/4885
US-20210060051-A1 COMBINED MODALITIES FOR NUCLEOSIDES AND/OR NADPH OXIDASE (NOX) INHIBITORS AS MYELOID-SPECIFIC ANTIVIRAL AGENTS NOX1, NOX3, NOX4 CASP3 1734/4885FAAH 1779/4885MGLL 887/4885
US-12268723-B2 Peptidomimetics for the treatment of coronavirus and picorna virus infections ACE2, SARS1, HAVCR2 CASP3 145/4885FAAH 2088/4885MGLL 2662/4885
US-20250114389-A1 NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS PNP, MTAP, NOP2 CASP3 281/4885FAAH 1588/4885MGLL 2798/4885
US-12239655-B2 Combined modalities for nucleosides and/or NADPH oxidase (NOX) inhibitors as myeloid-specific antiviral agents NOX1, NOX3, NOX4 CASP3 1450/4885FAAH 1558/4885MGLL 635/4885
US-20240238323-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES MTAP, PNP, SARS1 CASP3 310/4885FAAH 1355/4885MGLL 2091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.