⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL243025 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL20532707 | 0.97 | — | — | |
| Trifluoroacetic Acid SCHEMBL27610628 | 0.82 | L3MBTL1 (0.36) | — | |
| SCHEMBL659550 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL14743990 | 0.78 | HRH1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL26111974 | 0.78 | — | — | |
| SCHEMBL29086344 | 0.78 | CYP1B1 (0.32) | — | |
| SCHEMBL7704422 | 0.78 | CYP1B1 (0.32) | — | |
| SCHEMBL11005395 | 0.77 | — | — | |
| SCHEMBL8569658 | 0.75 | HRH1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213395-B | Pyrimidone acyl piperazine compound and preparation method and application thereof | 山东大学 | 2022-10-25 | — | — | CN | claimed |
| CN-110698420-B | Preparation method of 2-oxazole methylamine heterocyclic compound | 上海阿拉丁生化科技股份有限公司 | 2022-10-14 | — | — | CN | claimed |
| CN-114213395-A | Pyrimidone acyl piperazine compound and preparation method and application thereof | 山东大学 | 2022-03-22 | — | — | CN | claimed |
| CN-110698420-A | Preparation method of 2-oxazole methylamine heterocyclic compound | 上海阿拉丁生化科技股份有限公司 | 2020-01-17 | — | — | CN | claimed |
| EP-3510404-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | Pharmakea, Inc. (US) | 2019-07-17 | — | — | EP | claimed |
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. | 2019-06-27 | — | — | US | claimed |
| CN-109574948-A | A kind of preparation method of bis- (tertbutyloxycarbonyl) amine | 凯瑞斯德生化(苏州)有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-108884049-A | 2 inhibitor of quinolinone lysyloxidase sample and application thereof | 法玛克亚公司 | 2018-11-23 | — | — | CN | claimed |
| WO-2018048928-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | claimed |
| US-20140235548-A1 | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION | CLEAVE BIOSCIENCES, INC. (US) | 2014-08-21 | — | — | US | claimed |
| US-7462604-B2 | Hair growth promotor composition | LION CORPORATION (JP) | 2008-12-09 | — | — | US | claimed |
| US-20080207683-A1 | BIARYL-SUBSTITUTED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. | 2008-08-28 | — | — | US | claimed |
| WO-2008100622-A2 | BIARYL-SUBSTITUTED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | claimed |
| US-20080182870-A1 | PYRIDO(3,2-d)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-31 | — | — | US | claimed |
| WO-2008077651-A1 | PYRIDO(3,2-D)PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-07-03 | — | — | WO | claimed |
| WO-2008020024-A1 | NTETRAHYDROPYRIDOTHIOPHENE DERIVATIVES FOR THE TREATMENT OF CANCER | 4SC AG (DE) | 2008-02-21 | — | — | WO | claimed |
| US-20070116657-A1 | Hair growth promotor composition | LION CORPORATION (JP) | 2007-05-24 | — | — | US | claimed |
| EP-1671616-A1 | HAIR TONIC COMPOSITION | Lion Corporation (JP) | 2006-06-21 | — | — | EP | claimed |
| EP-0540854-B1 | Preparation for promoting hair growth | SANSHO SEIYAKU KK (JP) | 1998-01-21 | — | — | EP | claimed |
| EP-0540854-A2 | Preparation for promoting hair growth | Sansho Seiyaku Co., Ltd. (JP) | 1993-05-12 | — | — | EP | claimed |