SCHEMBL659550

SCHEMBL659550

NCCc1ncco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL14743990 0.98 HRH1 (0.34)
Hydrochloric Acid SCHEMBL26111974 0.98
SCHEMBL11005395 0.86
SCHEMBL29086344 0.85 CYP1B1 (0.32)
SCHEMBL8569658 0.85 HRH1 (0.40)
SCHEMBL5504566 0.83 HRH1 (0.43)
SCHEMBL245783 0.80
SCHEMBL7027055 0.78 FAAH (0.38)
SCHEMBL7022926 0.78 FAAH (0.38)
Hydrochloric Acid SCHEMBL243025 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102006862-A Compositions and controlled release dosage forms comprising weakly basic drugs EURAND INC 2011-04-06 CN claimed
US-5116856-A AMINOETHYLTHIAZOLE AND AMINOETHYLOXAZOLE DERIVATIVES AKZO N.V. (NL) 1992-05-26 US claimed
EP-0385525-A1 Aminoethylthiazole and aminoethyloxazole derivatives Akzo Nobel N.V. (NL) 1990-09-05 EP claimed
JP-2273664-A None JP disclosed
WO-2024054603-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. (US) 2024-03-14 WO disclosed
US-10703754-B2 Compounds and compositions for treating chemical warfare agent-induced injuries ELI LILLY AND COMPANY (US) 2020-07-07 US disclosed
US-10703754-B2 Compounds and compositions for treating chemical warfare agent-induced injuries ELI LILLY AND COMPANY (US) 2020-07-07 US disclosed
EP-3663295-A1 2,6-DIOXO,-2,3-DIHYDRO-1H-PURINE COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO THE ACTIVITY OF THE TRPA1 CHANNEL ELI LILLY AND CO. (US) 2020-06-10 EP disclosed
EP-3663295-A1 2,6-DIOXO,-2,3-DIHYDRO-1H-PURINE COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO THE ACTIVITY OF THE TRPA1 CHANNEL ELI LILLY AND CO. (US) 2020-06-10 EP disclosed
EP-3184527-B1 2,6-DIOXO,-2,3-DIHYDRO-1H-PURINE COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO THE ACTIVITY OF THE TRPA1 CHANNEL LILLY CO ELI (US) 2020-01-29 EP disclosed
EP-3184527-B1 2,6-DIOXO,-2,3-DIHYDRO-1H-PURINE COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO THE ACTIVITY OF THE TRPA1 CHANNEL LILLY CO ELI (US) 2020-01-29 EP disclosed
CN-1187385-C [2,5-disubstd.-1,4-phenylene oxide) block or graft copolymer NAT INTEGRATED INST OF IND TEC (JP) 2005-02-02 CN disclosed
CN-1321693-A [2,5-disubstd.-1,4-phenylene oxide) block or graft copolymer NAT INTEGRATED INST OF IND TEC (JP) 2001-11-14 CN disclosed
EP-0385525-B1 Aminoethylthiazole and aminoethyloxazole derivatives. AKZO NV (NL) 1994-04-13 EP disclosed
US-5116856-A AMINOETHYLTHIAZOLE AND AMINOETHYLOXAZOLE DERIVATIVES AKZO N.V. (NL) 1992-05-26 US disclosed
US-5116856-A AMINOETHYLTHIAZOLE AND AMINOETHYLOXAZOLE DERIVATIVES AKZO N.V. (NL) 1992-05-26 US disclosed
JP-H02273664-A AMINOETHYLTHIAZOLE AND AMINOETHYLOXAZOLE DERIVATIVE AKZO NV 1990-11-08 JP disclosed
EP-0385525-A1 Aminoethylthiazole and aminoethyloxazole derivatives Akzo Nobel N.V. (NL) 1990-09-05 EP disclosed
EP-0385525-A1 Aminoethylthiazole and aminoethyloxazole derivatives Akzo Nobel N.V. (NL) 1990-09-05 EP disclosed
EP-0385525-A1 Aminoethylthiazole and aminoethyloxazole derivatives Akzo Nobel N.V. (NL) 1990-09-05 EP disclosed