SCHEMBL2458247

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2584806	0.84	NQO2 (0.41)	—
	SCHEMBL2461065	0.80	KDM4E (0.40)	ALDH1A1KDM4EHPGDMAPTGLA
	SCHEMBL1136167	0.80	MAOB (0.39)	GAAL3MBTL1
	SCHEMBL2464368	0.79	BRD4 (0.44)	ALDH1A1KDM4EHPGDMAPTMAPK1
	SCHEMBL2461954	0.79	BRD4 (0.47)	ALDH1A1KDM4EHPGDMAPT
	SCHEMBL12160474	0.78	BRD4 (0.36)	ALDH1A1KDM4ESMN1; SMN2
	SCHEMBL2458167	0.71	BTK (0.41)	ALDH1A1KDM4EGLAGAAL3MBTL1
	SCHEMBL2463940	0.71	TNKS (0.40)	ALDH1A1KDM4EHPGDMAPTL3MBTL1
	SCHEMBL1136294	0.71	MAOB (0.37)	GAAPDE3BPDE3ALMNAMAPK1
	SCHEMBL1136157	0.70	MAPK13 (0.39)	ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.