Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692397 | 1.00 | POLB (0.48) | POLBESR2ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL5440206 | 0.88 | ALDH1A1 (0.43) | POLBESR2ALDH1A1HSD17B10MAPT | |
| SCHEMBL2458337 | 0.84 | POLB (0.50) | POLBESR2ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL28845278 | 0.83 | HSD17B10 (0.48) | POLBESR2ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL10935618 | 0.83 | POLB (0.67) | POLBESR2ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL397459 | 0.83 | POLB (0.48) | POLBALDH1A1HSD17B10MAPTCYP3A4 | |
| SCHEMBL31607617 | 0.83 | POLB (0.48) | POLBALDH1A1HSD17B10MAPTCYP3A4 | |
| SCHEMBL28424987 | 0.82 | POLB (0.48) | POLBESR2ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL3784859 | 0.80 | MAOA (0.45) | POLBALDH1A1CYP3A4TSHRNPC1 | |
| SCHEMBL31607612 | 0.80 | MAOA (0.45) | POLBALDH1A1CYP3A4TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024227104-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BRAF VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. (US) | 2024-10-31 | — | — | WO | disclosed |