Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 16/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24585279 | 0.88 | FOLH1 (0.78) | FOLH1CHRM2 | |
| SCHEMBL17676351 | 0.88 | FOLH1 (0.78) | FOLH1 | |
| SCHEMBL16901610 | 0.88 | FOLH1 (0.78) | FOLH1CHRM2 | |
| SCHEMBL22840033 | 0.85 | FOLH1 (0.76) | FOLH1 | |
| SCHEMBL22840077 | 0.85 | FOLH1 (0.79) | FOLH1 | |
| SCHEMBL22839976 | 0.82 | FOLH1 (0.61) | FOLH1CHRM2 | |
| SCHEMBL20312089 | 0.82 | FOLH1 (0.61) | FOLH1CHRM2 | |
| SCHEMBL24585284 | 0.81 | FOLH1 (0.61) | FOLH1 | |
| SCHEMBL22840014 | 0.78 | FOLH1 (0.78) | FOLH1 | |
| SCHEMBL20312213 | 0.78 | FOLH1 (0.78) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3699162-B1 | HETERODIMERS OF GLUTAMIC ACID | MOLECULAR INSIGHT PHARM INC (US) | 2022-06-29 | — | — | EP | disclosed |