SCHEMBL24587796

SCHEMBL24587796

NC(=O)c1ccc(C(=O)c2cc(N)cc(N)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
GAA P10253 1/20 0.50
PARP10 Q53GL7 5/20 0.48
PBRM1 Q86U86 1/20 0.48
PARP4 Q9UKK3 2/20 0.45
ALDH1A1 P00352 1/20 0.45
KMT2A Q03164 1/20 0.45
PARP15 Q460N3 1/20 0.45
PARP14 Q460N5 1/20 0.45
PARP16 Q8N5Y8 1/20 0.45
PARP11 Q9NR21 1/20 0.45
PARP1 P09874 2/20 0.44
POLB P06746 2/20 0.44
MAPT P10636 2/20 0.44
TSHR P16473 2/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C19 P33261 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27147137 0.86 PBRM1 (0.52) LMNAPARP10PBRM1ALDH1A1KMT2A
SCHEMBL19716260 0.84 PARP10 (0.65) LMNAGAAPARP10PARP4ALDH1A1
SCHEMBL8196675 0.83 PBRM1 (0.50) LMNAGAAPBRM1ALDH1A1KMT2A
SCHEMBL24587799 0.82 PBRM1 (0.58) LMNAPARP10PBRM1PARP15PARP14
SCHEMBL890399 0.81 CYP3A4 (0.44) LMNAPARP10PBRM1PARP4ALDH1A1
SCHEMBL27676963 0.81 SRD5A2 (0.57) LMNAPBRM1ALDH1A1KMT2AMAPT
SCHEMBL14237808 0.81 ALDH1A1 (0.67) LMNAGAAPBRM1ALDH1A1POLB
SCHEMBL4354499 0.80 PBRM1 (0.73) LMNAGAAPBRM1ALDH1A1KMT2A
Hydrochloric Acid SCHEMBL9563848 0.79 CYP3A4 (0.43) LMNAPARP10PBRM1PARP4ALDH1A1
SCHEMBL24587538 0.78 MKNK1 (0.55) PARP10CA2CA1MKNK1MKNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220204693-A1 Polyamide-Imide Copolymer and Film Containing the Same MICROCOSM TECHNOLOGY CO., LTD. (TW) 2022-06-30 US disclosed