SCHEMBL8196675

SCHEMBL8196675

Nc1cc(N)cc(C(=O)c2cc(N)cc(N)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.50
KDM4E B2RXH2 2/20 0.43
LMNA P02545 4/20 0.42
NPC1 O15118 2/20 0.42
MITF O75030 1/20 0.42
POLB P06746 1/20 0.42
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
DDO Q99489 1/20 0.41
USP2 O75604 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
MAPT P10636 2/20 0.37
HTT P42858 2/20 0.37
GAA P10253 1/20 0.37
MAPK1 P28482 1/20 0.37
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27147137 0.87 PBRM1 (0.52) PBRM1LMNANPC1MITFPOLB
SCHEMBL4354499 0.85 PBRM1 (0.73) PBRM1LMNANPC1MITFPOLB
SCHEMBL24587796 0.83 LMNA (0.50) PBRM1LMNANPC1MITFPOLB
SCHEMBL8992948 0.83 PBRM1 (0.77) PBRM1KDM4ELMNANPC1MITF
SCHEMBL7189753 0.82 CYP3A4 (0.55) PBRM1KDM4ELMNANPC1MITF
SCHEMBL987723 0.82 PBRM1 (0.42) PBRM1KDM4ELMNANPC1MITF
SCHEMBL8999884 0.82 CES2 (0.48) PBRM1KDM4ELMNANPC1MITF
SCHEMBL7184528 0.82 PBRM1 (0.42) PBRM1KDM4ELMNANPC1MITF
SCHEMBL7194390 0.82 ALDH1A1 (0.57) PBRM1KDM4ELMNANPC1MITF
SCHEMBL14237808 0.82 ALDH1A1 (0.67) PBRM1LMNANPC1MITFPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4555548-A Rubber composition for tire treads NIPPON ZEON CO. LTD. (JP) 1985-11-26 US claimed
US-4555547-A POLYBUTADIENE CONTAINING BENZOPHENONE OR THIOBENZOPHENONE UNITS INTHE CHAIN NIPPON ZEON CO. LTD. (JP) 1985-11-26 US claimed
US-4486583-A MOLDING MATERIALS, COATINGS HITACHI, LTD. (JP) 1984-12-04 US claimed
US-4390596-A POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER RHONE-POULENC INDUSTRIES (FR) 1983-06-28 US claimed
US-4238591-A BIS-MALEIMIDE, SILANEDIOL OR SILOXANE RHONE-POULENC INDUSTRIES (FR) 1980-12-09 US claimed
US-4225498-A Preparation of N-substituted oligo-imides RHONE-POULENC INDUSTRIES (FR) 1980-09-30 US claimed
CN-106633122-B High-performance polyphenylene derivatives/polyimide composite film preparation method 江西师范大学 2019-10-25 CN disclosed
CN-106478967-B The preparation method of high-performance polyphenylene derivatives film with benzimidazole linking point 江西师范大学 2019-04-02 CN disclosed
CN-106480530-B The preparation method of electrospinning high-performance polyphenylene derivatives nanofiber 江西师范大学 2018-12-21 CN disclosed
EP-2666814-B1 ELECTRICALLY CONDUCTIVE RUBBER ELASTOMER, CHARGING MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2018-03-14 EP disclosed
CN-106480530-A The preparation method of electrospinning high-performance poly benzene derivative nanofiber 江西师范大学 2017-03-08 CN disclosed
CN-106478967-A There is the preparation method of the high-performance poly benzene derivative thin film of benzimidazole linking point 江西师范大学 2017-03-08 CN disclosed
EP-2490077-B1 ELECTRIFICATING MEMBER AND ELECTROPHOTOGRAPHIC DEVICE CANON KK (JP) 2014-10-01 EP disclosed
US-4010220-A AMINO COMPOUND, POLYURETHANE ELASTOMER RHONE-POULENC INDUSTRIES (FR) 1977-03-01 US disclosed
US-4005154-A Curing 1,2-epoxy with prepolymer based on polyamines and oligomers possessing imide groups RHONE-POULENC S.A. (FR) 1977-01-25 US disclosed
US-3998904-A POLYAMINES WITH IMIDE GROUPS RHONE-POULENC S.A. (FR) 1976-12-21 US disclosed
US-3970714-A Heat-stable polyimide resin modified by unsaturated polyester RHONE-POULENC S.A. (FR) 1976-07-20 US disclosed
US-3966678-A Maleic anhydride-polyaldimine prepolymers RHONE-POULENC S.A. (FR) 1976-06-29 US disclosed
US-3950279-A DI- OR TRI-MALEIMIDE, AZOMETHINE, SOLID FOAMING AGENT CIBA-GEIGY CORPORATION (US) 1976-04-13 US disclosed
US-3947385-A Mixtures containing prepolymers, which can be converted to heat-resistant foamed plastics CIBA-GEIGY CORPORATION (US) 1976-03-30 US disclosed