SCHEMBL24587799

SCHEMBL24587799

NC(=O)c1cccc(C(=O)c2cc(N)cc(N)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.58
TDP1 Q9NUW8 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
ATM Q13315 1/20 0.52
PARP1 P09874 8/20 0.52
POLB P06746 2/20 0.50
NPC1 O15118 1/20 0.50
MITF O75030 1/20 0.50
LMNA P02545 1/20 0.50
TSHR P16473 2/20 0.45
CYP3A4 P08684 1/20 0.45
MAPT P10636 1/20 0.45
CYP2C19 P33261 1/20 0.45
RECQL P46063 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27263444 0.88 TDP1 (0.65) PBRM1TDP1L3MBTL1ATMPARP1
SCHEMBL8992948 0.86 PBRM1 (0.77) PBRM1TDP1L3MBTL1ATMPOLB
SCHEMBL2909580 0.84 PARP1 (0.59) PBRM1TDP1L3MBTL1PARP1POLB
SCHEMBL24587796 0.82 LMNA (0.50) PBRM1TDP1L3MBTL1PARP1POLB
SCHEMBL3105323 0.82 TDP1 (0.78) PBRM1TDP1L3MBTL1ATMPARP1
SCHEMBL9101086 0.81 PBRM1 (0.83) PBRM1TDP1L3MBTL1ATMPOLB
SCHEMBL29492479 0.81 PBRM1 (0.83) PBRM1TDP1L3MBTL1ATMPOLB
3-Aminobenzamide SCHEMBL16070 0.81 PBRM1 (0.63) PBRM1TDP1L3MBTL1PARP1POLB
SCHEMBL5611387 0.81 PARP1 (0.61) PBRM1TDP1L3MBTL1ATMPARP1
3-Aminobenzamide SCHEMBL27679552 0.81 PBRM1 (0.63) PBRM1TDP1L3MBTL1PARP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220204693-A1 Polyamide-Imide Copolymer and Film Containing the Same MICROCOSM TECHNOLOGY CO., LTD. (TW) 2022-06-30 US disclosed