Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GLP1R | P43220 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642848 | 0.80 | JAK1 (0.41) | KDM4EHPGDALDH1A1JAK1TYK2 | |
| SCHEMBL25598360 | 0.79 | LMNA (0.43) | KDM4EHPGDALDH1A1HSD17B10JAK1 | |
| SCHEMBL1641021 | 0.75 | MAPT (0.42) | KDM4EGAAMAPTNPSR1APOBEC3G | |
| SCHEMBL16230541 | 0.74 | GRM5 (0.46) | KDM4EHPGDALDH1A1HSD17B10GRM5 | |
| SCHEMBL20113072 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1GAAMAPTNPSR1 | |
| SCHEMBL4036232 | 0.72 | FDPS (0.54) | KDM4EALDH1A1HSD17B10MAPTNPSR1 | |
| SCHEMBL2122993 | 0.71 | ALDH1A1 (0.77) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL991579 | 0.71 | KDM4E (0.58) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL3825817 | 0.71 | GRM5 (0.43) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL7468377 | 0.71 | GRM5 (0.43) | KDM4EHPGDALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135430-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2022-06-30 | — | — | WO | disclosed |