SCHEMBL24588593

SCHEMBL24588593

COC(C)c1ccc(O)c(I)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.42
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
HIF1A Q16665 2/20 0.37
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
ALOX12 P18054 1/20 0.37
HTT P42858 1/20 0.37
RECQL P46063 4/20 0.35
TDP1 Q9NUW8 4/20 0.35
KDM4E B2RXH2 4/20 0.35
MAPT P10636 3/20 0.35
TSHR P16473 3/20 0.35
LMNA P02545 2/20 0.35
NFKB1 P19838 2/20 0.35
BLM P54132 2/20 0.35
ALOX15 P16050 1/20 0.35
THPO P40225 1/20 0.35
HSD17B10 Q99714 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29695968 1.00 FOLH1 (0.42) FOLH1AKR1C2AKR1C1HIF1AALDH1A1
SCHEMBL24589241 0.86 FOLH1 (0.40) FOLH1HIF1AALDH1A1GAAALOX12
SCHEMBL22991586 0.79 TTR (0.44) AKR1C2AKR1C1GAAHTTTDP1
SCHEMBL11112214 0.79 ESR1 (0.46) FOLH1HIF1AALDH1A1GAAALOX12
SCHEMBL788149 0.79 ALDH1A1 (0.57) FOLH1HIF1AALDH1A1GAAALOX12
SCHEMBL31275900 0.79 HIF1A (0.35) FOLH1HIF1AALDH1A1GAAALOX12
SCHEMBL24589210 0.78 TDP1 (0.45) AKR1C2AKR1C1HIF1AALDH1A1GAA
SCHEMBL7541393 0.78 TDP1 (0.47) HIF1AALDH1A1GAAALOX12HTT
SCHEMBL1758133 0.77 FOLH1 (0.35) FOLH1HIF1AALDH1A1GAAALOX12
SCHEMBL30474606 0.77 TSHR (0.59) GAATSHRNFKB1BLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348351-A1 COMPOUND, POLYMER, COMPOSITION, COMPOSITION FOR FILM FORMATION, PATTERN FORMATION METHOD, INSULATING FILM FORMATION METHOD, AND METHOD FOR PRODUCING COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-11-02 US disclosed
US-20230348351-A1 COMPOUND, POLYMER, COMPOSITION, COMPOSITION FOR FILM FORMATION, PATTERN FORMATION METHOD, INSULATING FILM FORMATION METHOD, AND METHOD FOR PRODUCING COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-11-02 US disclosed
US-20230348351-A1 COMPOUND, POLYMER, COMPOSITION, COMPOSITION FOR FILM FORMATION, PATTERN FORMATION METHOD, INSULATING FILM FORMATION METHOD, AND METHOD FOR PRODUCING COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-11-02 US disclosed
CN-116615405-A Compound, polymer, composition for film formation, method for forming pattern, method for forming insulating film, and method for producing compound 三菱瓦斯化学株式会社 2023-08-18 CN disclosed
WO-2022138670-A1 COMPOUND, POLYMER, COMPOSITION, FILM-FORMING COMPOSITION, PATTERN FORMATION METHOD, METHOD FOR FORMING INSULATING FILMS, AND COMPOUND PRODUCTION METHOD 三菱瓦斯化学株式会社 2022-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348351-A1 COMPOUND, POLYMER, COMPOSITION, COMPOSITION FOR FILM FORMATION, PATTERN FORMATION METHOD, INSULATING FILM FORMATION METHOD, AND METHOD FOR PRODUCING COMPOUND PHOSPHO1, RER1, RIF1 FOLH1 4796/4885AKR1C2 2295/4885AKR1C1 2274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.