Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 6/20 | 0.54 |
| ▸ | KIT | P10721 | 3/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | FLT1 | P17948 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12304343 | 0.90 | CSF1R (0.43) | CSF1RKITLCKPGRCHRM2 | |
| SCHEMBL14194677 | 0.85 | CSF1R (0.43) | CSF1RKITLCKPGRCHRM2 | |
| SCHEMBL2600091 | 0.85 | CSF1R (0.42) | CSF1RKITLCKPGRCHRM2 | |
| SCHEMBL12927740 | 0.82 | CSF1R (0.40) | CSF1RKITLCKPGRCHRM2 | |
| SCHEMBL12927530 | 0.79 | CYP3A4 (0.41) | CSF1RKITLCKPGRCHRM2 | |
| SCHEMBL14236264 | 0.76 | VNN1 (0.42) | SLC6A4 | |
| SCHEMBL12304080 | 0.76 | VNN1 (0.41) | SLC6A4CYP2C9 | |
| SCHEMBL12646947 | 0.75 | KDM4E (0.48) | CSF1RKIT | |
| SCHEMBL14235722 | 0.75 | HDAC3 (0.47) | ADORA3SLC6A4KDR | |
| SCHEMBL13056388 | 0.75 | CSF1R (0.52) | CSF1RKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581573-B1 | SYNTHESIS OF A COMPOUND THAT MODULATES KINASES | PLEXXIKON INC (US) | 2022-07-06 | — | — | EP | disclosed |