Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 3/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | GSR | P00390 | 2/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1769059 | 0.85 | PTGS1 (0.62) | SLC1A1SLC1A2GSRGRIK1GRIK2 | |
| SCHEMBL1769055 | 0.85 | PTGS1 (0.62) | SLC1A1SLC1A2GSRGRIK1GRIK2 | |
| SCHEMBL2459448 | 0.85 | PTGS1 (0.62) | SLC1A1SLC1A2GSRGRIK1GRIK2 | |
| SCHEMBL6294950 | 0.81 | PTGS1 (0.59) | SLC1A1SLC1A2GSRGRIK1GRIK2 | |
| SCHEMBL2210613 | 0.81 | PTGS1 (0.59) | SLC1A1SLC1A2GSRGRIK1GRIK2 | |
| SCHEMBL10136169 | 0.81 | SLC1A1 (0.50) | SLC1A1SLC1A2GSRGRIK1GRIK2 | |
| SCHEMBL29590846 | 0.80 | SLC1A1 (0.58) | SLC1A1SLC1A2GSRGRIK1GRIK2 | |
| SCHEMBL19774715 | 0.80 | SLC1A1 (0.48) | SLC1A1SLC1A2GSRGRIK1GRIK2 | |
| SCHEMBL29386612 | 0.79 | SLC1A1 (0.56) | SLC1A1SLC1A2GSRGRIK1GRIK2 | |
| Norvaline SCHEMBL2178341 | 0.77 | PTGS1 (0.55) | SLC1A1SLC1A2GSRGRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305346-B1 | ARTICLES EXHIBITING A BLOOD-COMPATIBLE SURFACE LAYER AND PROCESS FOR PROVIDING ARTICLES WITH SUCH A SURFACE LAYER | Astra Tech Aktiebolag (SE) | 1992-12-30 | — | — | EP | disclosed |