SCHEMBL24595409

SCHEMBL24595409

Cc1cccc2c1Oc1ccccc1N2C

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.44
ALDH1A1 P00352 4/20 0.44
P2RX4 Q99571 8/20 0.36
GAA P10253 2/20 0.35
HPGD P15428 2/20 0.35
RAB9A P51151 2/20 0.35
GLA P06280 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAOA P21397 1/20 0.35
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
AHR P35869 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24858834 0.86 MAOA (0.37) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL31067286 0.80 KDM4E (0.55) KDM4EALDH1A1P2RX4GAAHPGD
SCHEMBL47007 0.80 KDM4E (0.55) KDM4EALDH1A1P2RX4GAAHPGD
SCHEMBL24390084 0.79 P2RX4 (0.40) P2RX4SMN1; SMN2MAPTAHR
Hydrogen Sulfide SCHEMBL28845788 0.78 KDM4E (0.53) KDM4EALDH1A1P2RX4GAAHPGD
SCHEMBL24119538 0.77 P2RX4 (0.33) ALDH1A1P2RX4HPGDSMN1; SMN2AHR
SCHEMBL19844326 0.77 P2RX4 (0.37) ALDH1A1P2RX4SMN1; SMN2MAPT
SCHEMBL4012288 0.74 KDM4E (0.46) KDM4EALDH1A1P2RX4GAAHPGD
SCHEMBL12793340 0.74 KDM4E (0.41) KDM4EALDH1A1P2RX4GAAHPGD
SCHEMBL25137563 0.73 NOTUM (0.36) ALDH1A1HPGDSMN1; SMN2MAOALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11380847-B2 Thermally activated delayed fluorescent material, preparation method thereof, and electroluminescent device WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2022-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11380847-B2 Thermally activated delayed fluorescent material, preparation method thereof, and electroluminescent device ADGRF1, CD69, TRPA1 KDM4E 4761/4885ALDH1A1 133/4885P2RX4 145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.