SCHEMBL2459593

SCHEMBL2459593

CC(Cc1ccc(O)cc1)=c1ccc(=C(C)Cc2ccc(O)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.48
CAMK2A Q9UQM7 1/20 0.48
ESR1 P03372 4/20 0.46
ESR2 Q92731 2/20 0.46
FNTA P49354 1/20 0.43
FNTB P49356 1/20 0.43
ALDH1A1 P00352 1/20 0.43
PKM P14618 1/20 0.43
ABAT P80404 1/20 0.42
TAAR1 Q96RJ0 2/20 0.40
TMEM97 Q5BJF2 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
SLC6A2 P23975 1/20 0.40
KDM4E B2RXH2 1/20 0.39
F13A1 P00488 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3289055 0.79 ALDH1A1 (0.44) ALDH1A1
SCHEMBL11427025 0.78 CES1 (0.48) FNTAFNTBALDH1A1
SCHEMBL4099992 0.77 FNTA (0.50) CA2CAMK2AESR1ESR2FNTA
SCHEMBL8166438 0.77 CA2 (0.45) CA2CAMK2AESR1ESR2FNTA
SCHEMBL6522029 0.77 CA2 (0.54) CA2CAMK2AESR1ESR2FNTA
SCHEMBL10702370 0.75 CA2 (0.58) CA2CAMK2AESR1ESR2FNTA
SCHEMBL465583 0.73 CA2 (0.50) CA2CAMK2AESR1ESR2FNTA
SCHEMBL10629788 0.73 CA2 (0.60) CA2CAMK2AESR1ESR2FNTA
SCHEMBL4455 0.73 CA2 (0.62) CA2CAMK2AESR1ESR2FNTA
SCHEMBL9818131 0.73 CA2 (0.41) CA2CAMK2AESR1ESR2FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
JP-10067176-A None JP disclosed
JP-10315631-A None JP disclosed
EP-1805130-B1 METHOD FOR THE PREPARATION OF ALIPHATIC CHLOROFORMATES SABIC INNOVATIVE PLASTICS IP (NL) 2015-01-28 EP disclosed
EP-1945696-B1 METHOD OF IMPROVING ABRASION RESISTANCE OF PLASTIC ARTICLE USING FUNCTIONALIZED POLYMERS AND ARTICLE PRODUCED THEREBY SABIC INNOVATIVE PLASTICS IP (NL) 2013-07-31 EP disclosed
EP-1971631-B1 THERMALLY STABLE POLYCARBONATES, THERMOPLASTIC COMPOSITIONS THEREOF, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2011-09-21 EP disclosed
EP-1954741-B1 DIHYDROXY AROMATIC COMPOUNDS, METHODS FOR PREPARATION POLYMERS MADE THEREFROM, AND METHOD OF POLYMER PREPARATION SABIC INNOVATIVE PLASTICS IP (NL) 2010-12-22 EP disclosed
US-7855241-B2 Method of improving abrasion resistance of plastic article using nanoparticles and article produced thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-12-21 US disclosed
EP-1969058-B1 POLYCARBONATE COMPOSITIONS AND ARTICLES FORMED THEREFROM, WITH MATTE SURFACES AND HIGH LIGHT TRANSMISSIONS SABIC INNOVATIVE PLASTICS IP (NL) 2010-08-25 EP disclosed
US-7728059-B2 Polycarbonate compositions and articles formed therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-06-01 US disclosed
US-5756592-A FROM PHENOLIC RESINS ALLIEDSIGNAL, INC. (US) 1998-05-26 US disclosed
JP-H1067176-A THERMAL RECORDING BODY OJI PAPER CO LTD 1998-03-10 JP disclosed
EP-0557950-B1 Polyetherketones and polyethersulphones based on phenylindane and their use for optical systems HOECHST AG (DE) 1996-10-30 EP disclosed
US-5373081-A Radiation transparent HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-13 US disclosed
EP-0557950-A2 Polyetherketones and polyethersulphones based on phenylindane and their use for optical systems HOECHST AKTIENGESELLSCHAFT (DE) 1993-09-01 EP disclosed
US-5166304-A Liquid crystal device HOECHST AKTIENGESELLSCHAFT (DE) 1992-11-24 US disclosed
EP-0471703-A1 POLYARLYLETHER KETONES CONTAINING INDANE AND USE OF AMORPHOUS POLYARLYETHER KETONES IN OPTICAL SYSTEMS HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-26 EP disclosed
EP-0438810-A2 Use of polyaryletherketones as orientation layers HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-31 EP disclosed
WO-1990014378-A1 POLYARLYLETHER KETONES CONTAINING INDANE AND USE OF AMORPHOUS POLYARLYETHER KETONES IN OPTICAL SYSTEMS HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-29 WO disclosed