Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 2/20 | 0.37 |
| ▸ | ADH1C | P00326 | 2/20 | 0.37 |
| ▸ | ADH1A | P07327 | 2/20 | 0.37 |
| ▸ | ADH4 | P08319 | 2/20 | 0.37 |
| ▸ | ADH7 | P40394 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774986 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRKDM4EEPHX1HTT | |
| SCHEMBL7770667 | 0.97 | EPHX1 (0.46) | ALDH1A1TSHRKDM4EEPHX1HTT | |
| SCHEMBL21808586 | 0.97 | EPHX1 (0.46) | ALDH1A1TSHRKDM4EEPHX1HTT | |
| SCHEMBL7777007 | 0.97 | EPHX1 (0.46) | ALDH1A1TSHRKDM4EEPHX1HTT | |
| SCHEMBL25122655 | 0.97 | EPHX1 (0.46) | ALDH1A1TSHRKDM4EEPHX1HTT | |
| SCHEMBL7775120 | 0.97 | EPHX1 (0.46) | ALDH1A1TSHRKDM4EEPHX1HTT | |
| SCHEMBL19205925 | 0.97 | EPHX1 (0.46) | ALDH1A1TSHRKDM4EEPHX1HTT | |
| SCHEMBL24508589 | 0.97 | EPHX1 (0.46) | ALDH1A1TSHRKDM4EEPHX1HTT | |
| Hydrochloric Acid SCHEMBL22771630 | 0.97 | KDM4E (0.44) | ALDH1A1TSHRKDM4EEPHX1HTT | |
| SCHEMBL19963745 | 0.97 | EPHX1 (0.46) | ALDH1A1TSHRKDM4EEPHX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220211727-A1 | Mito-Magnolol Compounds and Methods of Synthesis and Use Thereof | AIX-MARSEILLE UNIVERSITE (FR) | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220211727-A1 | Mito-Magnolol Compounds and Methods of Synthesis and Use Thereof | CYP11B1, MFN2, CYP11B2 | ALDH1A1 3239/4885TSHR 4249/4885KDM4E 2515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.