Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20011271 | 0.77 | FDPS (0.44) | FDPSPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16479467 | 0.75 | FDPS (0.43) | FDPSALDH1A1HPGDCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL21774961 | 0.73 | FDPS (0.42) | FDPSALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL7037181 | 0.73 | LMNA (0.51) | FDPSPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24596179 | 0.72 | FDPS (0.41) | FDPSALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL8443845 | 0.72 | FDPS (0.41) | FDPSALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL23657200 | 0.69 | MEN1 (0.42) | FDPSPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21324046 | 0.68 | HTR2A (0.41) | HTR2CHTR2A | |
| SCHEMBL21324097 | 0.68 | HTR2C (0.37) | PDE4APDE4BPDE4CPDE4DHTR2C | |
| SCHEMBL11216301 | 0.68 | KMT2A (0.58) | FDPSHTR2CHTR2AHTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273146-A1 | TRICYCLIC COMPOUND AND USE THEREOF | Nanjing Zaiming Pharmaceutical Co., Ltd. (CN) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022143864-A1 | TRICYCLIC COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2022-07-07 | — | — | WO | disclosed |