Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20011271 | 0.77 | FDPS (0.44) | FDPSALDH1A1 | |
| SCHEMBL13403313 | 0.77 | MTNR1A (0.49) | FDPSHIF1A | |
| SCHEMBL16479467 | 0.75 | FDPS (0.43) | FDPSALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL7037181 | 0.73 | LMNA (0.51) | FDPSALDH1A1CYP1A2HPGD | |
| Hydrochloric Acid SCHEMBL21774961 | 0.73 | FDPS (0.42) | FDPSALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL8443845 | 0.72 | FDPS (0.41) | FDPSALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL24596147 | 0.72 | FDPS (0.41) | FDPSALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL23657200 | 0.69 | MEN1 (0.42) | FDPSALDH1A1HPGDHSD17B10 | |
| SCHEMBL20690973 | 0.68 | KMT2A (0.58) | FDPSALDH1A1 | |
| SCHEMBL6846986 | 0.67 | TDP1 (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273146-A1 | TRICYCLIC COMPOUND AND USE THEREOF | Nanjing Zaiming Pharmaceutical Co., Ltd. (CN) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022143864-A1 | TRICYCLIC COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2022-07-07 | — | — | WO | disclosed |