SCHEMBL2459658

SCHEMBL2459658

C=CC(=O)C[Si](OCC)(OCC)OCC

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2523856 0.79 TSHR (0.43) TSHRALDH1A1HPGD
SCHEMBL4757613 0.77 TSHR (0.44) TSHRALDH1A1HPGD
SCHEMBL954405 0.76 TSHR (0.40) TSHRALDH1A1HPGD
SCHEMBL27779858 0.74 TSHR (0.38) TSHRALDH1A1HPGD
Lithium Ion SCHEMBL3911402 0.73 FFAR3 (0.35) ALDH1A1
Potassium Ion SCHEMBL3915177 0.73 FFAR3 (0.35) ALDH1A1
SCHEMBL1093452 0.72 FFAR3 (0.38) ALDH1A1
SCHEMBL28132688 0.72 ALDH1A1 (0.45) TSHRALDH1A1
SCHEMBL14660004 0.71 TSHR (0.38) TSHRALDH1A1HPGD
Acrylic Acid SCHEMBL31139541 0.71 LMNA (0.40) TSHRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727982-A1 PRIMER COMPOSITION, ADHESIVE SYSTEM, AND RELATED PROCESSES 3M Innovative Properties Company (US) 2026-04-22 EP disclosed
EP-3585851-B1 AIR AND WATER BARRIER ARTICLE INCLUDING INELASTIC POROUS LAYER 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-04-01 EP disclosed
US-12403671-B2 Roll including air and water barrier article and method of using the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-09-02 US disclosed
EP-3108076-B1 EASY TO APPLY AIR AND WATER BARRIER ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-03-26 EP disclosed
US-12227936-B2 Tape, article including tape and composite layer, and related methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-02-18 US disclosed
WO-2024257046-A1 PRIMER COMPOSITION, ADHESIVE SYSTEM, AND RELATED PROCESSES 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-12-19 WO disclosed
EP-3337867-B1 AIR AND WATER BARRIER ARTICLE WITH POROUS LAYER AND LINER 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-04-10 EP disclosed
EP-3107712-B1 SELF SEALING ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-09-20 EP disclosed
US-11731394-B2 Air and water barrier articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-08-22 US disclosed
US-11512463-B2 Air and water barrier article with porous layer and liner 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-11-29 US disclosed
US-20170058510-A1 EASY TO APPLY AIR AND WATER BARRIER ARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2017-03-02 US disclosed
WO-2017031359-A1 AIR AND WATER BARRIER ARTICLE WITH POROUS LAYER AND LINER 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-02-23 WO disclosed
EP-3107712-A2 SELF SEALING ARTICLES 3M Innovative Properties Company (US) 2016-12-28 EP disclosed
EP-3108076-A1 EASY TO APPLY AIR AND WATER BARRIER ARTICLES 3M Innovative Properties Company (US) 2016-12-28 EP disclosed
WO-2016106273-A1 AIR AND WATER BARRIER ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-06-30 WO disclosed
WO-2016019248-A1 SELF SEALING PERMEABLE AIR BARRIER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-02-04 WO disclosed
US-20150368508-A1 COATING COMPOSITIONS AND ARTICLES MADE THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2015-12-24 US disclosed
EP-2951234-A2 COATING COMPOSITIONS AND ARTICLES MADE THEREFROM 3M Innovative Properties Company (US) 2015-12-09 EP disclosed
WO-2014121007-A2 COATING COMPOSITIONS AND ARTICLES MADE THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-08-07 WO disclosed
US-20110236586-A1 Method for Sealing Surfaces WACKER CHEMIE AG 2011-09-29 US disclosed