Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28569489 | 0.79 | ALDH1A1 (0.42) | TSHRALDH1A1 | |
| SCHEMBL2459658 | 0.77 | TSHR (0.46) | TSHRALDH1A1HPGD | |
| SCHEMBL2526183 | 0.77 | ALDH1A1 (0.41) | TSHRALDH1A1 | |
| SCHEMBL762567 | 0.74 | TSHR (0.38) | TSHRALDH1A1HPGD | |
| SCHEMBL14430090 | 0.73 | MEN1 (0.32) | ALDH1A1 | |
| SCHEMBL29613948 | 0.73 | TSHR (0.41) | TSHRALDH1A1HPGD | |
| SCHEMBL29057829 | 0.73 | ALDH1A1 (0.37) | TSHRALDH1A1 | |
| SCHEMBL7952686 | 0.72 | — | — | |
| SCHEMBL5072266 | 0.70 | TSHR (0.39) | TSHRALDH1A1HPGD | |
| SCHEMBL30540351 | 0.70 | TSHR (0.34) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008148805-A2 | KIT COMPRISING ALPHA-ALKOXYSILANE FUNCTIONALIZED COMPOUNDS X AND Y | L'OREAL (FR) | 2008-12-11 | — | — | WO | disclosed |