⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663916 | 0.97 | SHBG (0.41) | — | |
| SCHEMBL18432072 | 0.93 | SHBG (0.46) | — | |
| SCHEMBL4881997 | 0.86 | — | — | |
| SCHEMBL23595592 | 0.82 | SHBG (0.45) | — | |
| SCHEMBL2995478 | 0.79 | SHBG (0.50) | — | |
| SCHEMBL18051815 | 0.77 | DPP4 (0.41) | — | |
| SCHEMBL23188102 | 0.75 | TRPA1 (0.31) | — | |
| SCHEMBL19038425 | 0.75 | SHBG (0.42) | — | |
| SCHEMBL8009630 | 0.75 | — | — | |
| SCHEMBL12112275 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227446-A9 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | NANJING ZHENGXIANG PHARMACEUTICALS CO., LTD. (CN) | 2023-07-20 | — | — | US | disclosed |
| US-11542262-B2 | Phosphatidylinositol 3-kinase inhibitors | NANJING ZHENGXIANG PHARMACEUTICALS CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| US-20220220113-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | NANJING ZHENGXIANG PHARMACEUTICALS CO., LTD. (CN) | 2022-07-14 | — | — | US | disclosed |
| US-20220213096-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | NANJING ZHENGXIANG PHARMACEUTICALS CO LTD (CN) | 2022-07-07 | — | — | US | disclosed |